Prof. Dr. Tom N. Grossmann

Chair of Biomimetic Chemistry
Department of Chemistry and Pharmaceutical Sciences
Amsterdam Institute for Molecules, Medicines and Systems

Twitter-Link: @TomNGrossmann

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Congratulations to Christiane Stiller

December 8, 2016

Christiane successfully defended her PhD thesis “Peptid-vermittelte chemische Modifikation intrazellulärer Proteine”.

Congratulations to Adrian Glas

September 22, 2016

Adrian successfully defended his PhD thesis “Kohlenwasserstoff-verbrückte Peptide mit irregulärer Sekundärstruktur für die Inhibition von Protein-Protein-Interaktionen”.

Communication in ChemBioChem is online

September 6, 2016

“Constraining an irregular peptide secondary structure through ring-closing alkyne metathesis”

PM Cromm, K Wallraven, A Glas, D Bier, A Fürstner, C Ottmann, TN Grossmann*, DOI: 10.1002/cbic.201600362

Congratulations to Philipp Cromm

June 28, 2016

Philipp successfully defended his PhD thesis “Design und Synthese Peptid-basierter Inhibitoren für Protein-Protein-Interaktionen”.

Communication in Angewandte Chemie is online

June 28, 2016

Congratulations to the Etzkorn lab and thanks for having us onboard. This communication is featured on the inside cover.

“Selective protein hyperpolarization in cell lysates using targeted dynamic nuclear polarization”

T Viennet, A Viegas, A Kuepper, S Arens, V Gelev, O Petrov, TN Grossmann, H Heise, M Etzkorn*, DOI: 10.1002/anie.201603205

Article in ACS Chemical Biology is online

June 23, 2016

This article is featured on the cover.

“Protease-resistant and cell-permeable double-stapled peptides targeting the Rab8a GTPase”

PM Cromm, J Spiegel, P Küchler, L Dietrich, J Kriegesmann, M Wendt, RS Goody, H Waldmann*, TN Grossmann*, DOI: 10.1021/acschembio.6b00386

Article in Nature Communications is online

April 14, 2016

“Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides”

PM Cromm, S Schaubach, J Spiegel, A Fürstner*, TN Grossmann*, H Waldmann*, DOI: 10.1038/ncomms11300

ERC starting grant projects have been started

March 5, 2016

“Peptide-derived bioavailable macrocycles as inhibitors of protein-RNA and protein-protein interactions”

Congratulations to Jochen Spiegel and Chang‑Uk Lee

March 4, 2016

Jochen successfully defended his PhD thesis “Synthese und Evaluierung stabilisierter Bindungsepitope zur Adressierung kleiner GTPasen”.

Chang‑Uk successfully defended his PhD thesis “Structural basis for reversible, oxidative inhibition of PTEN phosphatase activity”.

Lab moves to the VU University Amsterdam

February 25, 2016

We just moved into the new labs. Personnel and equipment arrived savely.